Silvia Bonanno Selected Research

nusinersen

6/2022	Muscle quantitative MRI in adult SMA patients on nusinersen treatment: a longitudinal study.
6/2022	Quality of life assessment in adult spinal muscular atrophy patients treated with nusinersen.
3/2022	Sixth cranial nerve palsy after first intrathecal nusinersen administration.
1/2022	Identification of a cytokine profile in serum and cerebrospinal fluid of pediatric and adult spinal muscular atrophy patients and its modulation upon nusinersen treatment.
11/2020	Nusinersen safety and effects on motor function in adult spinal muscular atrophy type 2 and 3.

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Silvia Bonanno Research Topics

Disease

7	Myasthenia Gravis 01/2024 - 01/2011
6	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 11/2022 - 01/2020
5	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 12/2020 - 01/2015
3	Disease Progression 06/2022 - 01/2020
3	Inflammation (Inflammations) 12/2020 - 04/2016
2	Neuromuscular Diseases (Neuromuscular Disease) 02/2023 - 01/2020
2	Paresthesia (Dysesthesia) 11/2022 - 01/2018
2	Multiple Sclerosis 02/2022 - 03/2011
1	Atrophy 03/2024
1	Scoliosis 12/2023
1	Cough 12/2023
1	Muscular Diseases (Myopathy) 11/2023
1	Rare Diseases (Rare Disease) 01/2023
1	Abducens Nerve Diseases (Sixth Nerve Palsy) 03/2022
1	Muscular Atrophy (Muscle Atrophy) 05/2021
1	Myotonia 01/2021
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2021
1	Paralysis (Palsy) 01/2021
1	Channelopathies 01/2021
1	Neuroinflammatory Diseases 12/2020
1	Hypoxia (Hypoxemia) 01/2019
1	Glycogen Storage Disease Type II (Pompe's Disease) 01/2019
1	Fatigue 01/2018
1	Brain Neoplasms (Brain Tumor) 11/2017
1	Epilepsy (Aura) 11/2017
1	Communicable Diseases (Infectious Diseases) 11/2016
1	Autoimmune Diseases (Autoimmune Disease) 04/2016
1	Epstein-Barr Virus Infections 04/2016

Drug/Important Bio-Agent (IBA)

6	MicroRNAs (MicroRNA)IBA 02/2023 - 01/2015
5	nusinersenIBA 06/2022 - 11/2020
3	Biomarkers (Surrogate Marker)IBA 11/2023 - 01/2020
3	Toll-Like Receptors (Toll-Like Receptor)IBA 11/2023 - 04/2016
2	FM19G11IBA 03/2024 - 01/2019
2	Proteins (Proteins, Gene)FDA Link 11/2022 - 01/2020
2	AmifampridineIBA 11/2022 - 01/2018
2	Immunoglobulin G (IgG)IBA 02/2022 - 01/2019
2	AntibodiesIBA 01/2020 - 01/2019
2	AutoantibodiesIBA 01/2020 - 01/2011
2	Riluzole FDA LinkGeneric 01/2019 - 11/2017
2	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2019 - 11/2017
1	glucose-mannose-glucoseIBA 01/2024
1	Interleukin-7 (Interleukin 7)IBA 11/2023
1	4-chlorophenyl methyl sulfide (CPMS)IBA 01/2023
1	BNT162 VaccineIBA 02/2022
1	Immunosuppressive Agents (Immunosuppressants)IBA 02/2022
1	VaccinesIBA 02/2022
1	CytokinesIBA 01/2022
1	Ion Channels (Ion Channel)IBA 01/2021
1	ChemokinesIBA 12/2020
1	RNA (Ribonucleic Acid)IBA 01/2020
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2020
1	Therapeutic UsesIBA 01/2020
1	human GAA protein (Myozyme)FDA Link 01/2019
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 01/2019
1	Glutamic Acid (Glutamate)FDA Link 01/2019
1	Phosphotransferases (Kinase)IBA 01/2018
1	XenobioticsIBA 11/2017
1	EnzymesIBA 01/2017
1	Azathioprine (Imuran)FDA LinkGeneric 01/2017
1	Messenger RNA (mRNA)IBA 11/2016
1	Interleukin-4 (Interleukin 4)IBA 11/2016
1	Antiviral Agents (Antivirals)IBA 04/2016
1	Cholinergic ReceptorsIBA 04/2016
1	Dihydrotachysterol (AT 10)IBA 01/2016
1	AntigensIBA 01/2011

Therapy/Procedure

4	Therapeutics 06/2022 - 01/2011
2	Activities of Daily Living (ADL) 01/2024 - 01/2018
1	Walkers 12/2023
1	Denervation 12/2020
1	Precision Medicine 10/2019
1	Enzyme Replacement Therapy 01/2019
1	Drug Therapy (Chemotherapy) 11/2017